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Other forms of testosterone can have a more rapid effect, such as suspension (pure testosterone in an oil base)and transdermal (synthetic testosterone) preparations, though both of these do not have a long-lasting effect and may cause unwanted side effects.[48] Both the use of transdermal testosterone and testosterone gel are used to treat low testosterone and in some cases even high testosterone states (excess isoprostane levels (due to excessive consumption of testosterone-suppressing compounds) or the use of testosterone patches for longer periods of time are associated with a reduced level of circulating testosterone; the treatment of low testosterone should be performed once per year rather than once every seven years.[49][50] The main method of administering testosterone is injection, however there are newer forms of testosterone products such as gels and injections available today. These new products and methods may have faster effects. Supplementation and dose When it comes to increasing muscle mass and strength on an overall per-diet basis, supplementation has been shown to result in a significant, albeit transient, increase[51] in muscle mass and strength.[1] This is due to the increase in protein synthesis after 12-28 weeks of supplementation being greater than the baseline level prior to the intervention.[1] Both the protein synthesis and the net loss in water weight due to protein breakdown at 36 weeks of supplementation are greater during supplementation of 10-50 g per day (2-7g/kg; 1 lb of lean mass per day) than the baseline level of 3 g/kg (2-5g/lb) in the control group, whereas all other groups experienced the same decline.[1] This is thought to be due to the increase in protein synthesis following supplementation, since the increase in protein synthesis in the supplement group is not replicated in the control group due to the latter group experiencing the same decline; this may be due to there being less protein available during supplementation due to the muscle growth it promotes. It was noted that the increase in protein synthesis is not as severe as in other sources of training.[1] Additionally, other studies have noted a positive correlation between protein synthesis rates with weight training, and this correlation has been replicated with regards to protein synthesis rates.[52] The increases in lean mass associated with protein supplementation are correlated with training, however, it may be beneficial for bodybuilders, but it may not help bodybuilders with bodybuilding-specific training protocols alone. Thus supplementing with some protein or combining with food can enhance the positive effects of either for those individuals.[53] This method Similar articles:
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